The expressions of IL-33 and ST2 receptor in nervous system and their roles in pain / 中国医师杂志
Journal of Chinese Physician
; (12): 512-515, 2016.
Article
em Zh
| WPRIM
| ID: wpr-493012
Biblioteca responsável:
WPRO
ABSTRACT
Interleukin-33 (IL-33),a novel member of IL-1 family,is a multifunctional cytokine.IL-33 can act as a transcriptional repressor.It can also bind to growth stimulation expressed gene 2 protein (ST2) to induce the activation of some inflammatory cells.IL-33 is extensively expressed in nervous system.Some studies showed that the levels of IL-33 and ST2 were significantly changed in pain.Some reports demonstrated that the IL-33/ST2 signaling pathway played critical roles in them.This present article will review the biological characteristics of IL-33/ST2 and their expressions in nervous system and significance of interventional pain related diseases.
Texto completo:
1
Índice:
WPRIM
Idioma:
Zh
Revista:
Journal of Chinese Physician
Ano de publicação:
2016
Tipo de documento:
Article