Rapid Determination of Fifteen Elements in Ibuprofen Injection by ICP-MS / 中国药师
China Pharmacist
;
(12): 1000-1003, 2016.
Artigo
em Chinês
| WPRIM
| ID: wpr-493969
ABSTRACT
Objective:
To develop a method for the rapid determination of 15 elements such as Al,Ca,Cr,Mg,Zn,K,B,Sr, Cd,Ba,Pb,As,Sb,Na and Li in ibuprofen injection by ICP-MS.Methods:
After diluted by 2% nitric acid solution,the samples was determined directly by inductively coupled plasma mass spectrometry(ICP-MS)with the online internal standard to correct matrix interference and signal drifting.Results:
The detection limits of the method were ranged from 0. 031 to 5. 1 μg·L-1 . The average recoveries were within the range of 82. 6% -107% and RSDs were all less than 5% .Conclusion:
The method is rapid, accurate and highly sensitive,which can provide technical support for the quality control of ibuprofen injection.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
China Pharmacist
Ano de publicação:
2016
Tipo de documento:
Artigo
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