Randomized Controlled Trials on Compound Shenqi Soft Capsules in Children with Functional Dyspepsia / 中国药师

ABSTRACT

Objective:To evaluate the clinical effects of compound Shenqi soft capsules in the children with functional dyspepsia(FD). Methods:A stratified random,parallel,control and non-blind design was used,and the children with FD were randomly divided into groups after stratified by age. The children in the trial group were given compound Shenqi soft capsules,one capsule for the children with age under three and two capsules for the children with age over three,tid. The control group was treated with compound Shenqi granules,half a bag for the children with age under three and 1 bag for the children with age over three,tid. The treatment course was one month. The two groups were compared by the symptoms of bellyache,abdominal distension,early satiety,belching and nausea. The electrogastrogram was analyzed in two groups. Results:Compound Shenqi soft capsules could improve the symptoms of ballyache,abdominal distension,early satiety,belching and nausea obviously,increase normal rhythm and reduce bradygastria obviously,and there were significant differences compared with those before the treatment(P < 0. 05). The trial group was better than the control group in the improvement of ballyache,abdominal ditension,early satiety and bradygastria,and the difference was significant(P < 0. 05). The total effective rate of the trial group was 91. 9% ,while that of the control group was 78. 3% ,and the difference was statistically significant(P < 0. 05). Conclusion:The clinical effect of compound Shenqi soft capsules is satisfied without any adverse reaction during the test,suggesting the capsules are suitable for clinical application.