A Case of Essential Thrombocythemia in a Patient with Ankylosing Spondylitis Concomitantly Treated with Adalimumab
Journal of Rheumatic Diseases
;
: 51-55, 2015.
Artigo
em Inglês
| WPRIM
| ID: wpr-49428
ABSTRACT
Extreme thrombocytosis in patients with ankylosing spondylitis (AS) is rarely reported. Because the relationship between high disease activity and increased platelet counts is somewhat contradictory, severe thrombocytosis in AS patients can be secondary to infection, iron deficiency anemia, drug administration, and hematologic malignancies. Essential thrombocythemia (ET) is a rare acquired stem cell neoplasm characterized by overproduction of platelets by megakaryocytes in the bone marrow in the absence of other causes of thrombocytosis. There is no report in the literature regarding the association between AS and ET. We report on a case of a 34-year-old Korean man with active AS diagnosed as JAK2V617F mutation negative ET during adalimumab treatment.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Contagem de Plaquetas
/
Espondilite Anquilosante
/
Células-Tronco
/
Trombocitose
/
Medula Óssea
/
Megacariócitos
/
Fator de Necrose Tumoral alfa
/
Anemia Ferropriva
/
Neoplasias Hematológicas
/
Adalimumab
Limite:
Adulto
/
Humanos
Idioma:
Inglês
Revista:
Journal of Rheumatic Diseases
Ano de publicação:
2015
Tipo de documento:
Artigo
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