Traditional Chinese medicine in stem cell proliferation and tissue engineering / 中国组织工程研究

ABSTRACT

BACKGROUND:Some Chinese herbal ingredients produce the analogical and pharmacological effects equivalent to growth factors, which can promote cel proliferation as wel as tissue and organ recovery and regeneration. Additional y, they possess low price and relative stable physicochemical property. Thus, the applications of traditional Chinese medicine in tissue engineering has attracted more attentions of researchers al over the world. OBJECTIVE:To review the application of the traditional Chinese medicine in stem cel proliferation and tissue engineering. METHODS:A computer-based retrieval of PubMed and CNKI databases was performed for articles concerning the application of traditional Chinese medicine in stem cel proliferation and tissue engineering published from 1978 to 2015. The keywords were“the traditional Chinese medicine, tissue engineering, application, stem cel , anti-inflammatory, cross linking, surface modification, osteoblast, blood vessel”in English and Chinese, respectively. RESULTS AND CONCLUSION:Natural medicine and the traditional Chinese medicine are expected to be applied in tissue engineering as a surrogate of growth factor and antibiotics, which exert anti-inflammatory, angiogenesis, surface modification, anticoagulation and cross-linking roles as wel as promote proliferation and differentiation of stem cel s in tissue engineering.