Your browser doesn't support javascript.
loading
Preparation Technology Optimization of Salicylic Acid Drop Pills / 中国药师
China Pharmacist ; (12): 1200-1202, 2016.
Artigo em Chinês | WPRIM | ID: wpr-494903
ABSTRACT

Objective:

To study the influencing factors in the preparation of salicylic acid dropping pills , and determine the opti-mum preparation process .

Methods:

The environmental factors , heating temperature , matrix ratio and preparation steps of salicylic acid drop pills were observed .With pill weight difference , dissolution time and appearance quality as the indices , an orthogonal test was adopted to optimize the preparation process .

Results:

Salicylic acid and the matrix should be separately heated to prevent red ox-ide.The optimized preparation process of drop pills was as followsthe ratio of PEG 400 and PEG 6000 was 1∶5, the temperature of drug solution was 50℃, the dropping distance was 8 cm and the dropping rate was 70 drops per minute .

Conclusion:

The preparation process is simple and practicable .The pill weight difference , dissolution time and appearance quality all meet the quality require-ments.

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: China Pharmacist Ano de publicação: 2016 Tipo de documento: Artigo

Similares

MEDLINE

...
LILACS

LIS

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: China Pharmacist Ano de publicação: 2016 Tipo de documento: Artigo