Determination of Ferrous Succinate Tablets by Ion Chromatography / 中国药师
China Pharmacist
;
(12): 1194-1195, 2016.
Artigo
em Chinês
| WPRIM
| ID: wpr-494905
ABSTRACT
Objective:
To establish a method to determine ferrous succinate in ferrous succinate tablets .Methods:
Ion chromatog-raphy was performed on an IonPac AG19(4 mm ×250 mm)anion exchange chromatography column with a guard column of Ion Pac TM AG19( 4 mm ×50 mm);30.00 mmol· L-1 KOH was used as the isocratic eluent at a flow rate of 1.00 ml· min-1 with suppressed conductivity detection ( Curb75 mA) at the temperature of 30℃.The sample size was 25 μl .Results:
The linear range of succinic acid was 2.005 1-25.064 0μg· ml-1(r=0.999 5).The detection limit and quantitation limit was 0.12ng and 0.42ng, respectively. The recovery was 101.45%(RSD=0.43%, n=6).Conclusion:
The method is simple, rapid, accurate, reproducible and sensitive , and can be used to determine the ferrous succinate content in ferrous succinate tablets .
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
China Pharmacist
Ano de publicação:
2016
Tipo de documento:
Artigo
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