Function of Wnt/β-catenin signal pathway in renal tubular epithelial-mesenchymal transition regulation / 中华实用儿科临床杂志
Chinese Journal of Applied Clinical Pediatrics
; (24): 958-960, 2016.
Article
em Zh
| WPRIM
| ID: wpr-495248
Biblioteca responsável:
WPRO
ABSTRACT
Renal interstitial fibrosis is the common pathway for a variety of chronic renal disease to final stage renal failure,the main feature of it is the large accumulation of extra cellular matrix (ECM).Myofibroblasts is the major effector cells which lead to the synthesis of ECM,an important source of myofibroblasts is epithelial-mesenchymal transition(EMT).Wnt/β-catenin signaling pathway take part in the regulation of EMT,which make it become a potential site of anti-fibrosis therapy.
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1
Índice:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Applied Clinical Pediatrics
Ano de publicação:
2016
Tipo de documento:
Article