Comparative analysis to 64-slice CT coronary angiography quality by different injection rates of contrast agent / 中国医学装备

ABSTRACT

Objective:To explore the quality on 64-slice CT coronary angiography with different injection rates of contrast agent.Methods: 120 patients who have been diagnosed or suspected coronary atherosclerosis were selected in our hospital and were randomly divided into group A(4.5ml/s), group B(5.0ml/s) and group C(5.5ml/s), with 40 cases in each group. We observed CT attenuation values, image quality, and adverse reactions of the three groups.Results: There were significant differences in the ascending aorta, descending aorta, left main, left anterior descending artery, circumflex artery and the right coronary artery and other parts of the CT attenuation value (F=6.838,F=4.002,F=7.261,F=5.992,F=8.281,F=5.790,F=6.126;P<0.05). In image quality, the group B with 34 cases was significantly better than group A with 12 cases and group C with 20 cases (x2=9.632,x2=5.475;P<0.05). The rate of adverse reactions was 30%, 7.5% and 22.5% with 12 cases in group A, 3 cases in group B and 9 cases in group C. The rate in group B was significantly lower than in group A and group C (x2=12.985,x2=10.236;P<0.05).Conclusion: Through the application of the same concentration of the contrast agent and scan conditions to coronary angiography, we can get a good vascular enhancement and high quality imaging when the injection rate of contrast medium is 5ml/s, while incidence of adverse reactions may be reduced.