Comparative study of automatic biochemical analyzers in pipeline system / 国际检验医学杂志

ABSTRACT

Objective To perform the comparison and deviation analysis on the detection results among 7 automatic biochemical analyzers in the Abbott pipeline ,and to investigate the comparability of the same item results detected by different biochemical anal‐ysis systems .Methods The sixth analyzer was used as a reference ,the remaining six analyzers as the inspection systems .When the precision reached the requirement ,different concentrations of fresh mixed serum samples were detected by different instruments . The detection results of various items were performed the comparison and deviation analysis .The systematic error of medical deci‐sion level was served as the standard of methodological comparison .The clinical acceptability of different detection systems was judged with 1/2CLIA′88 allowable total error range as the standard .Results The SE% of TP ,ALB ,ALT ,AST ,GGT ,TBIL , BUN ,Cr ,GLU ,UA ,K ,Na ,P ,TC and TG were in the allowable ranges regulated by 1/2CLIA′88 ,the test results were in the clini‐cally acceptable levels ;the SE% of Cl and Ca were in the outside of the allowable ranges ,the results had no comparability ,but the results could reach the comparability by calibrating the self‐built detection system .Conclusion Conducting the comparison and de‐viation analysis of the results detected by different biochemical analyzers in the pipeline system at regular intervals is conducive to ensure the constancy of detection systems in the same laboratory and the traceability of their results to provide more accurate and reliable results for clinic .