Research progress in mechanism of coexistence of HBsAg and HBsAb in patients with HBV infection / 临床肝胆病杂志
Journal of Clinical Hepatology
;
(12): 375-378, 2014.
Artigo
em Chinês
| WPRIM
| ID: wpr-498947
ABSTRACT
Hepatitis B surface antibody (HBsAb)is formed in response to hepatitic B virus (HBV)infection,which is a typical character-istic of virus clearance.It is theoretically impossible to detect sequential expression of hepatitis B surface antigen (HBsAg)and HBsAb in the same patient.In recent years,however,cases of coexistence of HBsAg and HBsAb have been frequently reported.Clinically,coexis-tence of HBsAg and HBsAb is commonly seen in patients with chronic hepatitis B and those injected with hepatitis B vaccine or given high-dose monoclonal anti-HBs.The mechanism of this special phenomenon remains unclear.The relevant research findings in China and the rest of the world are summarized.Analysis shows that coexistence of HBsAg and HBsAb may be related to HBV S gene mutation,decreased binding force of HBsAb,etc.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Journal of Clinical Hepatology
Ano de publicação:
2014
Tipo de documento:
Artigo
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