Transitional cell carcinoma in the nasal cavity:a case report and review of the literature / 实用肿瘤学杂志

ABSTRACT

The primary transitional cell carcinoma in nasal cavity is clinically manifested by progessively increasing nasal decongestion,bloody and purulent secretion intermittent appear ,headaches,hearing loss.The macroscopic character showed that a medium gray red ground tissue .The tumor cells were arranged in nested ,pa-pillary by microscopy,the nucleus was round or oval shape ,the tumor cells was infiltrating growth,basophilia or bright.Immunhistochenmical showed that P63,CK5/6,CK18,UroplakinIII,CerbB -2,CEA were positive,Ki67 positive index was about S -100,Cga,Syn,Calponinare all tested negative .Nasal primary transitional cell carcino-ma is uncommon clinically ,and it is easy to misdiagnosed .Its diagnosis and differential diagnosis mainly depends on pathological histoloy and immunohistochenmical examination .