Enteral nutrition in pediatric Crohn's disease / 国际儿科学杂志

ABSTRACT

Crohn's disease (CD) is a major involvement terminal ileum and proximal colonic inflammatory bowel disease(IBD),by now it still cannot be cured.The main symptoms include abdominal pain,diarrhea,fever.With the progress of the disease,it can exhibit rectal bleeding,intestinal fistula intestinal obstruction,etc.Children with CD can display growth retardation and delayed puberty.The treatment of CD has been a hot spot that is being discussed by clinicians.The drug treatment has many side effects.The surgery has high recurrence rates and some complications.Enteral nutrition (EN) is a nuuitional way that we can mnsport nutriment into stomach or small intestine through oral or tube with few side effects.It can improve the poor nutrition of the patients,induction and maintenance conditions.EN has been widely used in clinical treatment of CD,especially in paediatric CD.This paper summarizes the importance of EN in treatment of CD,the main function,mechanisms,therapy and the factors of curative effect.