Study on the Chemical Constituents of Rabdosia rubescens / 中国药房

ABSTRACT

OBJECTIVE:To study the chemical constituents of Rabdosia rubescens. METHODS:The chemical constituents of R. rubescens were isolated and purified by silica gel,MCI GEL-CHP 20P,Sephadex LH-20 column and recrystallization,and their structure was identified on the base of spectral analysis and physicochemical properties. RESULTS:8 compounds were isolated in R. rubescens and identified as 24ζ-methyl-5α-lanosta-25-ketone(1),maoyecrystal F(2),rosthorin A(3),β-sitosterol(4),daucosterol (5),heptacosanoic acid (6),oridonin (7) and ponicidin (8). CONCLUSIONS:Compound 1 is isolated from R. genera for the first time and compound 3,6 are isolated from this plant for the first time. The research lays a certain foundation for the quality evaluation of R.rubescens.