Study on the Quality Standard for Jingbi Mixture / 中国药房
China Pharmacy
;
(12): 4721-4723, 2015.
Artigo
em Chinês
| WPRIM
| ID: wpr-500885
ABSTRACT
OBJECTIVE:
To establish quality standard for Jingbi mixture.METHODS:
TLC was adopted to identify the Notop-terygii Rhizoma et Radix,Aucklandia lappa and Pueraria lobata and determine the relative density and pH according to pharmaco-poeia method. HPLC was adopted to determine the content of puerarin. Column was XTerra? RP18 with mobile phase of acetoni-trile-0.05% phosphoric(1090,V/V)at flow rate of 1.0 ml/min,detection wavelength was 250 nm,column temperature was 25 ℃and volume injection was 10 μl.RESULTS:
TLC of Notopterygii Rhizoma et Radix,A. lappa and P. lobata showed clear spots and good separation. The relative density was 1.08,and pH was 4.5. The linear range of puerarin was 2.079-33.26 μg/ml(r=0.999 8);RSDs of precision,reproducibility and stability tests were lower than 1.0%;recovery was 99.50%-100.50%(RSD=0.42%,n=6).CONCLUSION:
The method is simple and good reproducibility,and can be used for the quality control of Jingbi mixture.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
China Pharmacy
Ano de publicação:
2015
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS