Compatible Stability of Cefmenoxime for Injection with Ganciclovir for Injection / 中国药房

ABSTRACT

OBJECTIVE:To study the compatible stability of Cefmenoxime for injection with Ganciclovir for injection in 0.9% Sodium chloride injection and 5% Glucose injection. METHODS:At room temperature,the appearance and pH of the mix-tures were observed after Cefmenoxime for injection was compatible with Ganciclovir for injection. HPLC method was adopted to determine the content of them. RESULTS:No significant change was noted for the mixture in appearance and pH value. The con-tent of ganciclovir was more than 98%,but that of cefmenoxime decreased to 75.33%. CONCLUSIONS:Cefmenoxime for injec-tion can not be mixed with Ganciclovir for injection in 0.9%Sodium chloride injection and 5%Glucose injection .