Your browser doesn't support javascript.
loading
Formula Optimization of Shengmai Dispersible Tablets by Uniform Design / 中国药师
China Pharmacist ; (12): 1980-1983, 2016.
Artigo em Chinês | WPRIM | ID: wpr-503308
ABSTRACT

Objective:

To explore the formula and preparation technology parameters of Shengmai dispersible tablets.

Methods:

With the granulation status, disintegration time, friability, taste and and so on as the testing indices, the formula and preparation tech-nology of Shengmai dispersion tablets were optimized by uniform design.

Results:

The optimized formula of Shengmai dispersible tab-lets was as follows25% extract powder, 58% MCC, 8% CCMC-Na, 4% CMS-Na, 2% L-HPC, 2% magnesium stearate and 1%sweetener. L-HPC and magnesium stearate were added after the granulation, and the tablet hardness was controlled at 25N. The opti-mized dispersible tablets could disintegrate uniformly within 3 min.

Conclusion:

The optimization of the prescription and preparation process parameters of Shengmai dispersing tablets is stable and reliable, and has good repeatability, and the process is feasible.

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: China Pharmacist Ano de publicação: 2016 Tipo de documento: Artigo

Similares

MEDLINE

...
LILACS

LIS

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: China Pharmacist Ano de publicação: 2016 Tipo de documento: Artigo