The Structure of the Internal Limiting Membrane Removed by Vitrectomy Using Tissue Plasminogen Activator
Journal of the Korean Ophthalmological Society
;
: 917-924, 2008.
Artigo
em Coreano
| WPRIM
| ID: wpr-50522
ABSTRACT
PURPOSE:
This study evaluated the effect of tissue plasminogen activator (TPA) on adhesion between the internal limiting membrane and the vitreous cortex in patients with diabetic macular edema.METHODS:
This retrospective study included 14 eyes of 14 patients with diabetic macular edema without posterior vitreous detachment. The fourteen eyes were divided into two groups. In the first group, vitrectomy and internal limiting membrane (ILM) removal were performed after intravitreal TPA 0.1 cc (50 ug) injection the day before vitrectomy and in the second group, vitrectomy and ILM removal were performed without previous injection of TPA. We observed the ILM using electron microscopy and verified the effects of the TPA.RESULTS:
Spontaneous posterior vitreous detachment occurred in 3 of 7 eyes in the first group. Internal limiting membranes removed by vitrectomy showed a smooth surface in 4 of 7 eyes in the first group and in 1 of 7 eyes in the second group. Seven eyes of the first group and 6 eyes of the second group revealed decreased foveal thickness and increased visual acuity 90 days postoperatively.CONCLUSIONS:
Preoperative intravitreal TPA injection was helpful for achieving posterior vitreous detachment and for decreasing possible postoperative complications involving in remnant vitreous cortex in patients with diabetic macular edema.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Complicações Pós-Operatórias
/
Vitrectomia
/
Microscopia Eletrônica
/
Acuidade Visual
/
Edema Macular
/
Estudos Retrospectivos
/
Ativador de Plasminogênio Tecidual
/
Descolamento do Vítreo
/
Olho
/
Membranas
Tipo de estudo:
Estudo observacional
Limite:
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Ophthalmological Society
Ano de publicação:
2008
Tipo de documento:
Artigo
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