Clinical consensus and progress of prophylactic cranial irradiation / 国际肿瘤学杂志

ABSTRACT

Prophylactic cranial irradiation is an effective means of dealing with brain metastasis of cancer,which can reduce the incidence of brain metastasis by killing the micrometastasis and then improve the prognosis.The effectiveness has been verified in small cell lung cancer,but the application is still in the exploration in non-small cell lung cancer (NSCLC) and breast cancer.Prophylactic cranial irradiation is expected to become the conventional treatment for patients with NSCLC of ⅢA-N2 stage after operation and adjuvant chemotherapy or breast cancer of epithelial growth factor receptor-positive after receiving trastuzumab.