Analysis of blood Hcy,hsCRP,vWF and NSE levels in patients with acute cerebral infarction / 心血管康复医学杂志

ABSTRACT

Objective:To explore the relationship among serum levels of homocysteine (Hcy) ,high sensitive C reac‐tive protein (hsCRP) ,von Willebrand factor (vWF) ,neuron-specific enolase (NSE) and acute cerebral infarction (ACI) induced by cerebral thrombosis .Methods:A total of 90 patients with ACI caused by cerebral thrombosis trea‐ted in our hospital were selected as ACI group ,another 90 healthy subjects undergoing physical examination simulta‐neously were regarded as healthy control group .Serum levels of Hcy ,hsCRP ,vWF and NSE were measured and compared between two groups .Results:Compared with healthy control group ,there were significant rise in serum levels of Hcy [ (10.25 ± 3.07)μmol/L vs .(20.48 ± 5.14)μmol/L] ,hsCRP [ (2.75 ± 0.67) mg/L vs .(10.66 ± 1.45) mg/L] ,vWF [(108.52 ± 38.28) ng/ml vs .(250.52 ± 21.99) ng/ml] ,NSE [(10.45 ± 1.27) ng/L vs .(17.89 ± 2.13) ng/L] in ACI group , P<0.05 all .Conclusion:Combined detections of serum homocysteine ,high sensitive C reactive protein ,von Willebrand factor and neuron -specific enolase can provide evidence for early diagnosis and treatment of acute cerebral infarction caused by cerebral thrombosis .