Clinical Observation of Xingpi Yang'er Granule in the Treatment of Primary Nocturnal Enuresis in Chil-dren / 中国药房
China Pharmacy
;
(12): 738-741, 2017.
Artigo
em Chinês
| WPRIM
| ID: wpr-507597
ABSTRACT
OBJECTIVE:
To observe the efficacy and safety of Xingpi yang'er granule in the treatment of primary nocturnal en-uresis in children.METHODS:
97 children with primary nocturnal enuresis were randomly divided into control group (46 cases) and observation group(51 cases). Control group received Racemic anisodamine tablet 0.5 mg/(kg.d),orally,once a day+Vitamin B1 tablet 10 mg,orally,3 times a day+Oryzanol tablet 10 mg,orally,3 times a day + Meclofenac hydrochloride capsule 0.1 g 30 min before going to bed,orally,once a day. Observation group was additionally received Xingpi yang'er granule 0.4 g for 5-6 years old and 0.6 g for 7-14 years old,3 times a day. They were treated for 4 weeks. Clinical efficacy,kidney Yang deficiency score,wake-up threshold,bladder capacity,bladder volume,BVWI,enuresis frequency,AVP,cAMP,cGMP,cAMP/cGMP be-fore and after treatment,recurrence rate and the incidence of adverse reactions in 2 groups were observed.RESULTS:
The total ef-fective rate in observation group was significantly higher than control group(P0.05);after 6 months,the total effective rate recur-rence rate in observation group was significantly lower than control group(P0.05).CONCLUSIONS:
Based on conventional treatment,Xingpi yang'er granule shows good efficacy and safety in the treatment of primary nocturnal enuresis in children,which can improve children's kidney Yang deficiency score,wake-up threshold and bladder capacity and serum AVP.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
China Pharmacy
Ano de publicação:
2017
Tipo de documento:
Artigo
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