Clinical efficacy of EGFR-TKIs for advanced squamous-cell lung cancer patients with EGFR mutations / 中国肿瘤临床
Chinese Journal of Clinical Oncology
;
(24): 1103-1105, 2016.
Artigo
em Chinês
| WPRIM
| ID: wpr-507817
ABSTRACT
Abstrac Objective:
To investigate the clinical efficacy of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) in the treatment of squamous-cell lung cancer patients with EGFR mutations.Methods:
We screened out seven patients who were diag-nosed with EGFR mutations and received EGFR-TKIs, such as gifitinib or erlotinib, from 2,317 squamous-cell lung cancer patients treat-ed at the Beijing Chest Hospital from January 2010 to July 2016.Results:
After using EGFR-TKIs, the objective response rate was 42.9%, the disease control rate was 100%, and the median progression-free survival was 6.1 months.Conclusion:
EGFR-TKIs exert a certain clinical curative effect on patients with EGFR mutations in squamous-cell lung cancer. However, given that only seven cases are pre-sented in this research group, more cases are needed for further research to verify the above conclusion.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Clinical Oncology
Ano de publicação:
2016
Tipo de documento:
Artigo
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