Advances in differential roles of HIF-1αand HIF-2αin the pathogenesis of hypoxic pulmonary hypertension / 中国药理学通报
Chinese Pharmacological Bulletin
; (12): 10-13, 2017.
Article
em Zh
| WPRIM
| ID: wpr-509262
Biblioteca responsável:
WPRO
ABSTRACT
Hypoxia-induced factors(HIFs)are the main regula-tors for the response of hypoxic environment.They are involved in hypoxia-related lung tissue cell damage and abnormal cell pro-liferation,among which,HIF-1αand HIF-2αplay the most im-prominant roles.This paper reviews the current researches of HIF-1αand HIF-2α,focusing on their structural and functional similarities and diversities,as well as their roles in the patho-genesis of hypoxic pulmonary hypertension.
Texto completo:
1
Índice:
WPRIM
Tipo de estudo:
Etiology_studies
Idioma:
Zh
Revista:
Chinese Pharmacological Bulletin
Ano de publicação:
2017
Tipo de documento:
Article