Application of cyclosporine A in noninfectious uveitis / 眼科新进展
Recent Advances in Ophthalmology
; (6): 293-297, 2017.
Article
em Zh
| WPRIM
| ID: wpr-511178
Biblioteca responsável:
WPRO
ABSTRACT
Uveitis is a kind of refractory blinding eye diseases.Noninfectious uveitis is an important part of uveitis,which is thought to be an autoimmune disease,and systemic immunosuppressive therapy is usually required to prevent visual loss.As a selective T-cell inhibitor,cyclosporine A is one of the most widely used immunosuppressants,and has obvious therapeutic effect on many kinds of uveitis.Cyclosporine A combined with glucocorticoid,other immunosuppressants or biological agents can improve the therapeutic effect and reduce the side effects.Recently,the inhibitory effect on glucocorticoid-resistant Th17 cells and topical application of cyclosporine A,show its advantage and potential in the treatment of noninfectious uveitis.
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1
Índice:
WPRIM
Idioma:
Zh
Revista:
Recent Advances in Ophthalmology
Ano de publicação:
2017
Tipo de documento:
Article