Effect of moxifloxacin and levofloxacin on the cure rate of urinary tract infection and the incidence of adverse reactions / 中国生化药物杂志

ABSTRACT

Objective To investigate the effect of moxifloxacin and levofloxacin on the treatment of urinary tract infection and the incidence of adverse reactions.Methods 92 cases of patients with urinary tract infection from January 2015 to September 2016 in Hangzhou cancer hospital were selected and randomly divided into group A and group B with 46 cases in each group.Group A were treated with moxifloxacin treatment,group B were treated with levofloxacin in the treatment,compared with the treatment of two groups of patients.Results The clinical effective rate and clinical cure rate of group A were significantly higher than those of group B,the difference was statistically significant(P<0.05),there was no significant difference in the incidence of adverse reactions and bacterial clearance between the two groups.The incidence of adverse reactions in group A was 10.87％,drug cost was 275.47 yuan,the cost effectiveness ratio of 3.17,the incidence of adverse reactions in group B was 13.04％,drug cost was 45.50 yuan,cost-effectiveness ratio of 0.59,there was no significant difference in the incidence of adverse reactions between the two groups; the cost of drug and cost-effectiveness of group A was significantly better than group B,the difference was statistically significant(P<0.05).Conclusion Moxifloxacin is more effective in the treatment of urinary tract infections,but levofloxacin has lower drug costs.