Clinical value of serum CA125 and HE4 combined with vaginal color Doppler in early screening of ovarian cancer among high-risk populations / 重庆医学
Chongqing Medicine
; (36): 1613-1615, 2017.
Article
em Zh
| WPRIM
| ID: wpr-511943
Biblioteca responsável:
WPRO
ABSTRACT
Objective To explore the clinical value of serum CA125 and HE4 combined with transvaginal color Doppler(TVCD)examination in early screening of ovarian cancer among high-risk populations.Methods The included research subjects were divided into 3 groups:100 cases in the healthy group,80 cases in the high-risk group and 32 cases in the ovarian cancer group.The serum CA125 and HE4 levels and ultrasonic scores were compared among 3 groups.Results The HE4 and CA125 levels and ultrasound scores in the ovarian cancer group were significantly increased compared with the other two groups,the difference was statistically significant(P<0.01);the positive detection rate of CA125 plus HE4 levels combined with ultrasonic examination in the high-risk group was higher than that of other detection method(P<0.05);the sensitivity and specificity of CA125+HE4 combined with vaginal ultrasound screening were obviously higher than those of other screening method,the difference was statistically significant(P<0.05);the specificity of HE4 was significantly higher than that of CA125,but its sensitivity was lower than that of CA125(P<0.05).Conclusion CA125 and HE4 combined with TVCD is helpful for early screening of ovarian cancer in high-risk populations,easy to save medical cost and improves its detection rate.
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Índice:
WPRIM
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Screening_studies
Idioma:
Zh
Revista:
Chongqing Medicine
Ano de publicação:
2017
Tipo de documento:
Article