The protecting effect on liver of Vietnam’s Linh chi mushroom (ganoderma lucidum) on rat suffering from expreimental liver function failure

ABSTRACT

On white rats, high doses of paracetanol (2g/kg of body mass) and carbonetetrachloride (CCl4 –1.4ml/kg body mass administrated orally) increased dramatically serum transaminase AST and ALT, reduced liver capacity of cholesterol and total protein synthetizations. Granulous degeneration, lipid degeneration and necrosis focus were observed pathohistologically. Linh chi mushroom fluid extracts with the dose of 4g/kg of body mass reversed these biochemical indicators and restored nearly normally the damaged tissues. Similar results were obtained with the oral dose of 25mg Silimarin brand name preparation/kg body mass.