Korean Guidelines for the Diagnosis and Management of Dry Eye: Development and Validation of Clinical Efficacy
Korean Journal of Ophthalmology
;
: 197-206, 2014.
Artigo
em Inglês
| WPRIM
| ID: wpr-51387
ABSTRACT
PURPOSE:
To evaluate the clinical efficacy of newly developed guidelines for the diagnosis and management of dry eye.METHODS:
This retrospective, multi-center, non-randomized, observational study included a total of 1,612 patients with dry eye disease who initially visited the clinics from March 2010 to August 2010. Korean guidelines for the diagnosis and management of dry eye were newly developed from concise, expert-consensus recommendations. Severity levels at initial and final visits were determined using the guidelines in patients with 90 +/- 7 days of follow-up visits (n = 526). Groups with different clinical outcomes were compared with respect to clinical parameters, treatment modalities, and guideline compliance. Main outcome measures were ocular and visual symptoms, ocular surface disease index, global assessment by patient and physician, tear film break-up time, Schirmer-1 test score, ocular surface staining score at initial and final visits, clinical outcome after three months of treatment, and guideline compliance.RESULTS:
Severity level was reduced in 47.37% of patients treated as recommended by the guidelines. Younger age (odd ratio [OR], 0.984; p = 0.044), higher severity level at initial visit, compliance to treatment recommendation (OR, 1.832; p = 0.047), and use of topical cyclosporine (OR, 1.838; p = 0.011) were significantly associated with improved clinical outcomes.CONCLUSIONS:
Korean guidelines for the diagnosis and management of dry eye can be used as a valid and effective tool for the treatment of dry eye disease.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Soluções Oftálmicas
/
Síndromes do Olho Seco
/
Estudos Retrospectivos
/
Seguimentos
/
Morbidade
/
Guias de Prática Clínica como Assunto
/
Gerenciamento Clínico
/
Técnicas de Diagnóstico Oftalmológico
/
República da Coreia
/
Imunossupressores
Tipo de estudo:
Estudo diagnóstico
/
Guia de Prática Clínica
/
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Limite:
Adulto
/
Idoso
/
Aged80
/
Feminino
/
Humanos
/
Masculino
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Korean Journal of Ophthalmology
Ano de publicação:
2014
Tipo de documento:
Artigo
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