Biomechanical analysis of dynamic simulation of meniscus under different loading conditions / 中国组织工程研究

ABSTRACT

BACKGROUND: At present, the meniscus injury is very common, and can lead to serious injury of the knee joint.Meniscus biomechanics has been reported, but no studies have concerned the biomechanical characteristics of the meniscus in knee buckling during gait under different loading conditions.OBJECTIVE: To simulate and analyze the biomechanical characteristics of the knee joint meniscus under different loading conditions using finite element method.METHODS: Based on the knee magnetic resonance imaging data of normal adult volunteers, three-dimensional finite element model of knee joint was reconstructed. The stress, distribution and changes in the meniscus under different flexion angles were analyzed at 300 N, 400 N and 500 N.RESULTS AND CONCLUSION: (1) Under the respectively loading conditions of 500 N, 400 N and 300 N, the maximum stress point all from the place of posterior horn of medial meniscus anterior surface of tibia moved to the posterior margin of the anterior tibial attachment of the lateral meniscus, and the maximum displacement all from the place of midpoint of the inner edge of the medial meniscus moved to front outer edge of the lateral meniscus during normal dynamic buckling process of 0°, 30°, 60° and 90°, and the range of stress and displacement of lateral meniscus was greater than that of medial meniscus; simultaneously, the distribution range of stress and displacement was proportional to the size of the loading and the angle of the buckling. (2) The three-dimensional finite element model of the knee joint meniscus can be used to effectively dynamically simulate the distribution of force and displacement under different loading conditions, and can provide evidence for speculation of the mechanism of the injury of the meniscus in clinic.