The incidence and risk factors of pelvic insufficiency fracture in patients with cervical cancer after intensity-modulated radiotherapy / 中华放射医学与防护杂志
Chinese Journal of Radiological Medicine and Protection
;
(12): 193-198, 2017.
Artigo
em Chinês
| WPRIM
| ID: wpr-515216
ABSTRACT
Objective To analyze the incidence and risk factors of pelvic insufficiency fractures (PIF) in patients with cervical cancer who received pelvic intensity-modulated radiotherapy.Methods This study a retrospective review of all patients was performed with cervical cancer who received pelvic intensity-modulated radiotherapy at our institution from November 2013 to December 2015,and the incidence and risk factors of insufficiency fractures were analyzed.Results Among the 104 patients,16 (with a total of 31 lesions) were diagnosed with pelvic insufficiency fracture.The occurrence rate of pelvic insufficiency was 15.4%.Ten patients (62.5%) had multiple fractures and five patients (31%) complained of pain.All patients' pain was relieved by rest or analgesic drugs.Insufficiency fractures were detected at a median of 6.5 months (range 1-16) from radiotherapy completion.The distribution of PIFs was followedsacral had 16 cases (51.6%),sacroiliac joint had 7 cases (22.6%),iliac had 6 cases (19.4%),femoral head had 1 case (3.2%) and pubis had 1 case (3.2%).Univariate analysis and multiple analysis showed that postmenopausal status and low body weight (≤55 kg) were thought to be risk factors for PIF(P < 0.05).Subgroup analysis also confirmed that postmenopausal status was a risk factor for PIF (P < 0.05) in postoperative cervical cancer patients after pelvic intensity-modulated radiation therapy.Conclusions Cervical cancer patients with menopausal status and low body weight (≤55 kg) are at some risk for the development of PIF after pelvic intensity-modulated radiotherapy.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo de etiologia
/
Estudo de incidência
/
Fatores de risco
Idioma:
Chinês
Revista:
Chinese Journal of Radiological Medicine and Protection
Ano de publicação:
2017
Tipo de documento:
Artigo
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