A new low elastic modulus of beta titanium alloy Ti2448 spinal pedicle screw fixation affects thoracic stability:biomechanical analysis / 中国组织工程研究

ABSTRACT

BACKGROUND:A new type of medical titanium alloy Ti2448 (Ti-24Nb-4Zr-7.9Sn) is by far the lowest initial modulus of titanium alloy, with the initial modulus of about 40 GPa, the average Young's modulus<20 GPa, and tensile strength of about 900 MPa;human tissue biocompatibility and mechanical compatibility are excellent. OBJECTIVE:To investigate the biomechanical properties of a new low elastic modulus spinal pedicle screw fixation system and compare it with Ti6Al4V pedicle screw. METHODS:Totally 60 fresh human cadaveric thoracic vertebrae were randomly selectedon one side, pedicle new low modulus Ti2448 pedicle screws, as the experimental group;on the other side, pedicle screw Ti6Al4V, as control group. The maximum bending load and maximum load displacement, maximum torque and maximum axial pul ing force of the two groups were detected. RESULTS AND CONCLUSION:There was no significant difference in the maximum bending load, maximum load displacement, maximum torque and maximum pulling force between the two groups. The results show that the maximum bending strength, the maximum torque and maximum pul out force in low elastic modulus of Ti2448 pedicle screw fixation system are consistent with the Ti6Al4V screws, which can meet the needs of internal fixation on spinal biomechanics strength.