Effect of Ca~(2+) concentration on the ventricular fibrillation threshold and its relation to the levels of cAMP, cGMP and ATP in rat ischemic heart / 中国病理生理杂志

ABSTRACT

The purpose of this study was to investigate the effects of different Ca~(2+) concentrations on the ventricular fibrillation threshold(VFT) in the acute reg- ional ischemic isolated, paced rat hearts and to investigate their relations to the levels of cAMP, cGMP and ATP in the myocardium. It was demonstrated that a positive correlation was observed between [Ca~(2+)] and the percentage of VFT lowered in the ischemic hearts (r=0.7998, P