Effect of Pollen Compound Tablets on Atherosclerosis in Rabbits / 昆明医科大学学报

ABSTRACT

An experimental atherosclerotic model was established by feeding rabbits with 0.5 gram cholesterol every day.17 rabbits were divided by random pairing in to two groups, one feeding with pollen compound tablets in addition but the other not. The preventive effect of pollen compound tablets on the development of atherosclerosis was evaluated. The results showed that the cholesterol level in the aortic wall, the surface area of the aortic atherosclerotic lesions and its severity, and the frequency and severity of the coronary arterial lesions were diminished markedly in the rabbits fed with pollen compound tablets. The results also indicated that this anti-atherosclerosis effect was related to the decrease of lipids, apoipoprotein B and peroxide lipids in serum and the inhibition of the platelet aggregation rate. It also related to the increase of prostacyclin in serum.