Preliminary Study on the Mode of Inheritance of Male Pattern Alopecia (MPA) / 昆明医科大学学报

ABSTRACT

95 probands' family frees of MPA have been studied by the methods of simple segregation analysis and estimation of heritability. The result shows that MPA may be caused by different hereditary patterns. In the families with affected parents and vertical transmission. MPA may be caused by an autosomal dominant (AD) gene, making up 56.84% (AD) and 2.11% (reduced penetrance). It also shows that MPA may be due to polygenic inheritance.