Exploration on Correlative Mechanism Between Intensity of Blood - activation Stasis - removal and Metastasis of Stomach Carcinoma of Deficient Type of Both Qi and Blood / 中医杂志

ABSTRACT

Retrospective study was made on the correlation between the intensity of blood - activation stasis -removal drugs in Yiqi Shengxue Recipe and the metastasis of qi - blood deficiency type of stomach carcinoma, with a positive result, demonstrating that the rat's of its metastasis increased with the intensity of the drugs. It is suggested that this might be due to the decrease of platelet count and its aggregation, low plama fibrinogen . and increase of fibrinolysis in these patients. Moreover, medern pharmacology shows that most drug and recipes of blood - activation stasis -removal inhibit the platelet aggregation, blood coagulation, and increase fibrinolysis. It is suggested that, in such patients, when the pletelet count and their aggregation are markedly decreased, prolonged blood coagulation time with high FDP. the intensity of the drugs should be lowered so as to avoid metastasis.