Change of calcimn metabolism in liver mitochondria and its effect on mitochondrial respiratory function fol- lowing biliary obstruction / 中华肝胆外科杂志
Chinese Journal of Hepatobiliary Surgery
;
(12)1998.
Artigo
em Chinês
| WPRIM
| ID: wpr-516815
ABSTRACT
Objective To explore the change of liver mitochondrial calcium metabolism and its effect on mitochondrial respiratory function.Methods The model of dog biliary obstruction was made by bile duct ligation. Mitochondria were obtained by differential centfifugation.Mitochondrial calcium content,calcium uptake rate and respiratory function were observed and compared.Results Liver mitochondrial calcium content was increased sig- nificantly,calcium uptake rate and respiratory function were obviously reduced after biliary obstruction.Mitochon- drial calcium content was highly negatively correlated with mitochondrial respiratory function (P
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Hepatobiliary Surgery
Ano de publicação:
1998
Tipo de documento:
Artigo
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