Clinical Significance of Thrombo Molecular Markers in Blood-stasis Syndrome in Diabetes Mellitus / 中医杂志

ABSTRACT

By applying the thrombo pre molecular markers, including plasmal GMP - 140, tPA, PAI - I TAT, PAP, ET, their correlation with blood stasis type diabetes were explored. Results showed that, the diabetic with blood -stasis type revealed the activation of platelets, injury of endothelial cells, changes of fibrinolysin. Their plasmal GMP-140, TAT, PAP, ET were all higher than that of the control group, indicating that the activation of platelets, injury of endothelial cells, and changes in the balance of blood coagulation/fibrinolysis are likely to benefit the incidence of blood stasis. The pathophysiological mechanism in blood stasis type diabetes is related to the changes in platelet, endothelial cells, blood coagulation and fibrinolysis.