Effect of membrane environment at high temperature on delayed rectifier K+ channel in hypothalamus neurons / 中国病理生理杂志

ABSTRACT

AIM: To observe the effect of high temperature on the delayed rectifier K+ channel(I K) in hypothalamus neurons METHODS: The kinetic properties of I K were measured by cell-attached mode of patche-clamp technique RESULTS: The conductance, long-term open constant(? o2 ) and open probability(Po) of I K increased with increase of temperature ( P