Analyses of Genetic Epidemiology of Psoriasis Vulgaris / 中华皮肤科杂志
Chinese Journal of Dermatology
;
(12)1994.
Artigo
em Chinês
| WPRIM
| ID: wpr-517400
ABSTRACT
Objective To investigate the effects of genetic factors on the onset of psoriasis. Methods Seven hundred and twenty patients with psoriasis vulgaris were studied by questionnaire. Results① For the male and female patients, the peak ages of the first onset were 20~ 29 and 10~ 19 years, respectively, and the average ages were 27.57? 12.18 and 23.01? 12.40 years, respectively.② In 720 psoriatics, 212 cases (29.4% ) reported to have a family history of psoriasis. The age of onset was earlier in man with family history than that in man without family history (P0.05).④ The heritabilities of psoriasis were 71.07%? 2.05% in first degree relatives and 36.77%? 5.17% in second degree relatives. Conclusion The results show that psoriasis vulgaris may be a multigenic inheritable disease, and the genetic factors play an important role in the pathogenesis.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo de rastreamento
Idioma:
Chinês
Revista:
Chinese Journal of Dermatology
Ano de publicação:
1994
Tipo de documento:
Artigo
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