Effects of hippocampus NE or Ach system disfunction on P3-like potential in rats / 中国病理生理杂志
Chinese Journal of Pathophysiology
;
(12)2000.
Artigo
em Chinês
| WPRIM
| ID: wpr-517906
ABSTRACT
AIM:
To study the change in cognitive function in derogative state of different neurotransmitter by mensurating P300 amplitude and latency.METHODS:
Acetylcholine (ACh) system was disfunctioned by severing fimbrial-fornix(FF) transaction and Norepinephrine (NE) system impaired by injection of 6-hydroxysopamine into the bilateral dorsal noradrenergic bundle in DG. Then Y-type maze test and elicitation of P3-like latency were carried out separately before and after the all models were built.RESULTS:
In both experimental groups, P3-like latency was prolonged significantly compared with the control and had positive correlation with indices of Y-maze test(EN,TRT).CONCLUSION:
ACh and NE are important in the production and conformity of P300.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Pathophysiology
Ano de publicação:
2000
Tipo de documento:
Artigo
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