The expression and significance of oncogene C-erbB-2,p16,nm23H1 in exhepatic bile duct cancer / 中国普通外科杂志

ABSTRACT

Objective This study was to investigate correlations between the expression of oncogene c erbB 2 , p16 and nm23H1 and the development of the carcinoma. Methods Immunohistochemical S P method was used to examine the expression of oncogenes in 46 cholangiocarcinoma cases and 13 cases of benign bile duct lesions. The relationship between the expression and clinical pathology was analyzed. Results The positive rate of C erbB 2 in cholangiocarcinoma increased significantly ( P