The Effect of Sera from Intrahepatic Cholestasis of Pregnancy on the Expressions of ICAM-1 and P-selectin on the HUVEC / 中华围产医学杂志

ABSTRACT

Objective To study in vitro ICAM 1 and P selectin expressions of endothelial cells treated with sera from intrahepatic cholestasis of pregnancy (ICP). Methods HUVEC were cultured and stimulated with sera, and the expression of ICAM 1 and P selectin by flow cytometry were measured. Results (1) The expressions of ICAM 1 of P selectin on the HUVEC surface after stimulation with sera from women with ICP were higher than those of without stimulation in normal pregnancy ( P