Effects of glucocorticoids on the glucocorticoid receptor ? and ? mRNA expression / 中国病理生理杂志
Chinese Journal of Pathophysiology
;
(12)1986.
Artigo
em Chinês
| WPRIM
| ID: wpr-518848
ABSTRACT
AIM:
To clarify the effects of glucocorticoids on the messenger RNA expression of glucocorticoid receptor (GR? and GR?).METHODS:
messenger RNA of GR ? and GR? were determined by quantitive RT-PCR.RESULTS:
Besides GR? mRNA, GR? mRNA is also expressed in human osteosarcoma cell line HOS-8603, human ovarian carcinoma cell line 3AO and human peripheral white blood cells. After administration of dexamethasone, both GR? mRNA and GR? mRNA were down-regulated in a time-dependent and dose-dependent manner.CONCLUSION:
GR? expresses in various kinds of human tissue cells. The expression of GR? is regulated by glucocorticoids.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Pathophysiology
Ano de publicação:
1986
Tipo de documento:
Artigo
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