Pathophysiological effect of excess iodine on the thyroid / 中国普通外科杂志

ABSTRACT

Objective To determine the relationship between excess iodine and the thyroid diseases. Methods The effects of excess iodine on rat thyroid and human thyroid cell were observed . Results All the rats in the experimmental group had diffuse colloidal goiter.With the increase of iodine levels,the relative and absolute weight of the goiter increased and revealed atypical abnormal hyperplasia as compared with the control group. The heights of thyroid follicular epithelial cells were decreased and the areas of thyroid follicular spaces were enlarged(p