Determination of Chloramphenicol and Dexamethasone Sodium Phosphate in Ear Drops by HPLC / 中国药房
China Pharmacy
;
(12)2001.
Artigo
em Chinês
| WPRIM
| ID: wpr-519428
ABSTRACT
OBJECTIVE:
To establish a method for the simultaneous determination of chloramphenicol and dexamethasone sodium phosphate in ear drops by HPLCMETHODS:
Chloramphenicol and dexamethasone sodium phosphate were separated with a mobile phase of methanol-phosphate buffer solution(0 34% KH2PO4 solution)(60∶40,v/v,1 0ml/min)on Kromasil C8 column and detected at 240nmRESULTS:
Good linearity appeared in the concentration of chloramphenicol 100~500?g/ml,r=0 9 999,the recovery was 98 5%~100 8%,RSD≤1 5%;and good linearity showed in the concentration of dexamethasone sodium phosphate 16~80?g/ml,r=0 9 990,the recovery was 98 8%~100 6%,RSD≤2 0%CONCLUSION:
This method can simultaneously detect both ingredients in the ear drops
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
China Pharmacy
Ano de publicação:
2001
Tipo de documento:
Artigo
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