G-protein Coupled Estrogen Receptor (GPER/GPR30) and Women's Health
Journal of Menopausal Medicine
;
: 79-81, 2015.
Artigo
em Inglês
| WPRIM
| ID: wpr-51973
ABSTRACT
Estrogen - the female sexual hormone playing the most important role - plays a physiologically significant role, not only regulating in cell signals with second messenger but also being active in regulating transcription. Estrogen receptor (ER) which is a protein accepting estrogen not only play the role of a transcription factor combining with other genes to regulate their activity like other nuclear receptors but also performs external activities, combining with DNA, etc. G-protein coupled ER (GPER) that has been recently discovered exists as 7-membrane and has non-genomic (rapid) signaling. These functions, however, are not extensively addressed. This paper discusses the roles of GPER and its physiological mechanism.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fatores de Transcrição
/
DNA
/
Sistemas do Segundo Mensageiro
/
Saúde da Mulher
/
Receptores Citoplasmáticos e Nucleares
/
Proteínas de Ligação ao GTP
/
Genômica
/
Estradiol
/
Estrogênios
Limite:
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Journal of Menopausal Medicine
Ano de publicação:
2015
Tipo de documento:
Artigo
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