Observation of Application of Reptilase to Abdominal Surgery in Perioperative Period / 中国药房

ABSTRACT

OBJECTIVE:To study the hemostatic effect of reptilase on abdominal operations in perioperative period.METH-ODSThe study was conducted in 66 patients.They were randomly divided into 2 groupsreptilase group(n=35) and control group(n=31).In reptilase group,the reptilase was given in pre-operative,post-operative and intraoperative period and in control group,other commonly-used hemostants were given in the same way as in reptilase group.The amount of bleeding,the content of D-D in venous blood,the quantity of postoperative bloody drainage were compared between 2 groups.RESULTS:The amount of intraoperative bleeding,postoperative contents of D-D in venous blood and the quantity of bloody drainage in reptilase and control group were(312.1?30.3)ml,(521.5?29.2)ml(P