Expression of Costimulatory Molecules CD80and CD86on Peripheral Blood Lymphocytes in Patients With Systemic Lupus Erythematosus / 中华皮肤科杂志

ABSTRACT

Objective To investigate the expression of costimulatory molecules CD80and CD86on peripheral blood lymphocytes(PBLC)in patients with systemic lupus erythematosus(SLE)and its significance.Methods The expression of CD80and CD86on PBLC was measured by flow cytometric assay in30patients with SLE and25normal controls.Results Expression of CD86on PBLC in patients with SLE was significantly lower than that of normal controls(P