Initial Electrocardiographic Changes associated with Clinical Severity in Acute Organophosphate Poisoning
Journal of The Korean Society of Clinical Toxicology
;
: 69-76, 2009.
Artigo
em Coreano
| WPRIM
| ID: wpr-52180
ABSTRACT
PURPOSE:
Various electrocardiogram (ECG) changes can occur in patients with acute organophosphate poisoning (OPP) and may be associated with the clinical severity of poisoning. The present study aimed to evaluate the extent and frequency of ECG changes and cardiac manifestations, and their association with acute OPP clinical severity.METHODS:
Seventy-two adult patients admitted to our emergency department with a diagnosis of acute OPP were studied retrospectively. ECG changes and cardiac manifestations at admission were evaluated. ECG changes between respiratory failure (RF) group and no respiratory failure (no RF) groups were compared.RESULTS:
Prolongation of QTc interval (n=40, 55.6%) was the most common ECG change, followed by sinus tachycardia (n=36, 50.0%). ST-T wave changes such as ST segment elevation or depression and T wave change (inversion or non-specific change) were evident in 16 patients (22.2%). Prolongation of QTc interval was significantly higher in the RF group compared with the no RF group (p=0.03), but was not an independent predictor for RF in acute OPP (OR; 4.00, 95% CI; 0.70-23.12, p=0.12).CONCLUSION:
While patients with acute OPP can display ECG changes that include prolongation of QTc interval, sinus tachycardia, and ST-T wave changes at admission, these changes are not predictors of respiratory failure.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fenilpropionatos
/
Insuficiência Respiratória
/
Taquicardia Sinusal
/
Estudos Retrospectivos
/
Depressão
/
Eletrocardiografia
/
Emergências
/
Intoxicação por Organofosfatos
Tipo de estudo:
Estudo observacional
Limite:
Adulto
/
Humanos
Idioma:
Coreano
Revista:
Journal of The Korean Society of Clinical Toxicology
Ano de publicação:
2009
Tipo de documento:
Artigo
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