The expansion of CD4~+ T lymphocytes in rats with colitis induced by 2, 4, 6- trinitrobenzene sulphonic acid / 中国病理生理杂志
Chinese Journal of Pathophysiology
;
(12)1986.
Artigo
em Chinês
| WPRIM
| ID: wpr-522298
ABSTRACT
AIM:
To study on the expansion of CD~(4+) T lymphocytes isolated from rats with colitis induced by 2,4,6-trinitrobenzene sulphonic acid (TNBS).METHODS:
The numeration and protein expression of CD~(4+) T lymphocytes had been performed by immunohistological analysis, flow cytometry and Western-blot.RESULTS:
The numeration of CD4+ T cells and the protein expression of CD~(4+) T lymphocytes increased significantly in rats with colitis induced by 2,4,6-trinitrobenzene sulphonic acid.CONCLUSION:
Expansion of CD~(4+) T lymphocytes in TNBS-induced colitis provides us a simple and reducible animal model for research of the new target of therapeutic drug.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Pathophysiology
Ano de publicação:
1986
Tipo de documento:
Artigo
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